What is our Endo-Cannabinoid System?
Remember back in elementary school when they teach you about our body systems and they briefly mention the endocannabinoid system? I always remember trying to say that word as a youngin and always laughing at myself. Come to find out this ends cannabinoid system would play such a large role in my life quite literally and figuratively.
Lets take a quick dive into the basics of our endo-cannbinoid system. Our Endo-Cannabinoid System includes our appetite, immune system, pain management, sleep, memory and our emotional state as human beings. We have two primary endocannabinoid receptors have been identified: CB1, first cloned in 1990; and CB2, cloned in 1993. CB1 receptors are found predominantly in the brain and nervous system, as well as in peripheral organs and tissues, and are the main molecular target of the endocannabinoid lingad (binding molecule), anadamine, as well as its mimetic phytocannabinoid,THC. One other main endocannabinoid is 2-Arachidonoylglycerol (2-AG) which is active at both cannabinoid receptors, along with its own mimetic phytocannabinoid, CBD. 2-AG and CBD are involved in the regulation of appetite, immune system functions and pain management.
The endocannabinoid system (ECS) is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. Known as "the body’s own cannabinoid system" the ECS is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory, and in mediating the psychoactive effects of cannabis. The ECS is also involved in voluntary exercise and may be related to the evolution of the runner's high in human beings and related aspects of motivation or reward for locomotor activity in other animals. Recent studies from the UK and Israel have shown that there are around 140 + cannabinoid receptors in our body.
ECS is pretty much all that we are made up of. We naturally produce it and we need CBDs in our system daily just as we are told to take Vitamin C, Zinc, Magnesium, Calcium and much more. We NEED this in our daily lives.,
Different receptors for different compounds link to different receptor points:
- CBGA (Cannabigerolic acid)
- THCA (Δ9-tetrahydrocannabinolic acid)
- CBDA (Cannabidiolic acid)
- CBCA (Cannabichromenenic acid)
- CBGVA (Cannabigerovarinic acid)
- THCVA (Tetrahydrocanabivarinic acid)
- CBDVA (Cannabidivarinic acid)
- CBCVA (Cannabichromevarinic acid)